cd31 (Proteintech)
Structured Review

Cd31, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 261 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+cd31/Cd31+Polyclonal+antibody/pmc13620297-381-14-15
Average 96 stars, based on 261 article reviews
Images
1) Product Images from "uPAR ‐Targeting T Cell Engager Exerts Senolytic Effects in Mice and Non‐Human Primates With Serum Aminotransferase Activity as a Safety Monitor"
Article Title: uPAR ‐Targeting T Cell Engager Exerts Senolytic Effects in Mice and Non‐Human Primates With Serum Aminotransferase Activity as a Safety Monitor
Journal: Aging Cell
doi: 10.1111/acel.70742
Figure Legend Snippet: mGFD‐CD3 induces hepatotoxicity by targeting hepatic endothelial cells in mice. (A) H&E analysis performed at 24 h post‐injection of BiTE in the liver tissues of naturally aged mice. Scale bar, 30 μm (original) and 15 μm (magnified). (B) Immunofluorescence analysis was conducted on liver, lung, and kidney samples from naturally aged mice collected 24 h post‐BiTE injection ( n = 6 view field per each treatment group). Scale bar, 30 μm. (C) Immunofluorescence analysis of liver samples of naturally aged mice taken 4 h post‐injection of BiTE to examine the colocalization of BiTE, CD31, and uPAR. Scale bar, 30 μm (original) and 15 μm (magnified). (D) Immunofluorescence analysis to examine the colocalization of CD31 and uPAR in the liver tissues of wild type mice (WT) and uPAR knockout mice; ( n = 3 mice per treatment group). Scale bar, 30 μm. (E) Levels of AST and ALT in serum samples from mice before and after BiTE injection were determined with a Biochemical Analyzer; ( n = 3 mice per treatment group). Data is presented as mean ± SD and analyzed by unpaired two‐tailed Student's t ‐test with Welch's correction. *** p ≤ 0.001.
Techniques Used: Analysis, Injection, Immunofluorescence, Knock-Out, Blood/Plasma/Serum Samples, Two Tailed Test
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